Best Probiotic Drops for Newborns
Looking for the best probiotic drops to nurture your newborn’s tummy**? Navigating the sea of options can feel overwhelming, but we've rounded up the top choices that promise gentle, effective support for your baby's delicate digestion. Dive into our concise guide and find the perfect probiotic boost for your little one's well-being.
Great Value Selection: Mommy's Bliss Probiotic Drops

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Effective for colic relief |
Easy squeeze dropper |
Clean ingredients |
Mommy's Bliss Baby Probiotic Drops earns its "Great Value Selection" badge thanks to its highly researched probiotic strain and pediatrician endorsement.
The drops come in a convenient squeeze bottle, making daily dosing straightforward—even during those hectic mornings.
While some babies might find the flavor a tad challenging, many parents appreciate the clean, simple ingredients and effective soothing relief for colic and tummy troubles.
The large purchase volume makes it budget-friendly without sacrificing quality, and the normal cloudy appearance is no cause for concern.
Overall, a reliable and accessible probiotic option for your little one's health.
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Best for Colic Relief: Culturelle Probiotics

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Helps soothe fussiness |
Supports healthy digestion |
Contains Vitamin D |
Culturelle Baby Colic plus Soothing Probiotics is our pick for the best for colic relief.
It features gentle, safe strains that naturally help reduce fussiness and crying linked to digestive upset, giving tired parents some much-needed relief.
Plus, each dose provides 100% of the daily value of Vitamin D, supporting your baby's bone development.
The drops are super easy to administer—just five drops a day directly into the mouth or on a spoon.
While the bottle is small and a bit pricey, its soothing benefits make it a trustworthy addition to your baby's routine.
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Best for Digestive Support: Culturelle Baby Drops

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Clinically studied probiotics |
Gentle, safe ingredients |
Easy to administer |
Culturelle Baby Probiotic Drops + Vitamin D is our top pick for Digestive Support because it combines clinically studied probiotic strains with the recommended daily dose of Vitamin D.
This powerful combo helps promote a healthy gut and immune support in newborns, all in a gentle, drug-free formula.
The drops are super easy to use—just shake, dispense, and let your little one enjoy.
While the small bottle size may mean refilling sooner, the gradual, noticeable improvements in tummy comfort make it worth it.
Overall, it’s a safe, reliable choice for parents wanting the best for their baby’s development.
Be sure to also check out the best hair oil for newborn for more options! Also, here is the price history so you know exactly when to buy!

Best for Sensitive Tummies: MaryRuth Organics Probiotic Drops

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Supports digestion |
Organic & Non-GMO |
Easy to administer |
The MaryRuth Organics USDA Organic Infant Liquid Probiotic Drops truly stand out as best for sensitive tummies.
Its USDA Organic, vegan, and allergen-free formula offers a gentle yet effective way to support your baby’s digestion without any fuss.
The liquid format makes it easy to give once daily—just a few drops directly into the mouth or mixed into a beverage.
Plus, it's Clean Label Project Certified, ensuring high-quality ingredients.
While the dosage info could be clearer and it has a plain flavor, its organic credentials make it a top choice for health-conscious parents seeking a trustworthy, gentle probiotic.
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BioGaia

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Soothes colic and fussiness |
Safe for newborns |
Naturally found in breast milk |
BioGaia Baby is a trusted name backed by over 20 years of research in soothing colic and gassy tummies.
It’s completely safe for newborns from day one, whether they’re breastfed, bottle-fed, or both.
The probiotic ingredients are naturally found in breast milk, making it a gentle, chemical-free solution.
While results may take a few days to fully show, many parents find relief from fussiness, spit-ups, and occasional constipation.
Plus, it’s free from common allergens like dairy, soy, and gluten—no artificial colors or flavors.
A solid choice for those seeking a natural, scientifically validated remedy.
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Lovebug Probiotics

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Includes vitamin D |
Improves digestion |
Award-winning quality |
Lovebug’s probiotic drops are formulated specifically for babies ages 0-12 months, addressing common issues like colic, diarrhea, and constipation with 6 clinically studied strains.
Plus, they contain vitamin D to support healthy growth and immune function.
The fact that they're USDA Organic Certified and sugar-free ensures you're giving your little one a pure, safe supplement without added synthetic ingredients.
Although the drops dispense quickly—so a gentle hand is needed—they're award-winning, trusted by many parents, and made in the USA.
Overall, a reliable choice for a healthy start!
Be sure to also check out the best pacifiers for breastfed newborns for more options! Also, here is the price history so you know exactly when to buy!

Wellements Organic Baby Probiotics Probiotic Drops for Newborns

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Supports digestive health |
Odorless and tasteless |
Organic and safe ingredients |
The Wellements Organic Probiotic Drops stand out for their gently formulated blend of high-quality ingredients like LactoSpore Bacillus coagulans and organic MCT oil, making them safe for delicate little tummies.
They’re odorless and tasteless, which helps when you’re trying to get a fussy baby to accept drops with ease.
The refrigeration requirement adds a layer of freshness and potency, though it does mean extra storage steps.
Overall, this probiotic combines organic purity with effectiveness, making it a reliable choice for supporting your newborn’s gut health—although it might stretch your budget a bit.
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Mommy's Bliss

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Easy to administer |
Taste-free drops |
Supports digestion |
Mommy's Bliss Baby Probiotic Drops + Vitamin D are gentle and safe for even the tiniest newborns, thanks to the most researched probiotic strain.
The tasteless drops make administration a breeze for busy parents, supporting your baby's digestion and overall immunity.
While there’s a slight melting risk if not stored properly, with careful handling, these drops stay effective and easy to use.
Overall, they're a reliable, pediatrician-recommended choice that brings a little extra comfort to your little one's tummy.
Perfect for parents looking for convenience and proven quality.
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Culturelle Baby Digestive Calm

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Clinically studied probiotics |
Gentle, safe ingredients |
Easy to administer |
Culturelle Baby Digestive Calm + Comfort Drops is the #1 pediatrician-recommended probiotic brand, making it a trustworthy choice for new parents.
With two of the most clinically studied probiotics, it’s designed to gently ease those tummy troubles and reduce fussiness caused by digestion issues.
The method of administration is straightforward—just 5 drops a day, which can be added to a spoon, bottle, or directly into the baby’s mouth.
While the dropper could be a bit more precise, overall, this formula provides a safe, effective way to support your baby’s digestive health from birth onward.
Be sure to also check out the best soft books for infants for more options! Also, here is the price history so you know exactly when to buy!

BioGaia Protectis Baby Probiotic Drops for Newborns

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Soothes colic & gas |
Safe for newborns |
Contains breast milk probiotics |
BioGaia Baby with Vitamin D is a gentle, science-backed choice that helps soothe fussiness, colic, and gas—common challenges for newborns.
Since it’s safe from day one, it’s perfect whether you're breastfeeding or bottle-feeding.
We love that it contains naturally occurring breast milk probiotics, making it a more organic solution.
While it may pose a challenge to administer daily and is a bit on the pricier side, its natural efficacy and safety make it a go-to for many parents seeking quick relief for their little ones’ tummy troubles.
Be sure to also check out the best pool float for pregnancy for more options! Also, here is the price history so you know exactly when to buy!

Pink Stork Baby Probiotic

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Supports digestion and immunity |
Easy to administer |
Unflavored and baby-friendly |
Pink Stork Baby Probiotic Drops stand out with their trusted formula containing 1 billion CFU of Lactobacillus rhamnosus, a well-researched probiotic recommended by pediatricians.
The no-drip syringe makes administering just 0.5 mL daily a breeze — perfect for tiny cheeks or mixing into food and milk.
Parents love that it's unflavored and baby-friendly, encouraging consistent use without fuss.
Plus, the product's vegan, gluten-free, and free from artificial additives give peace of mind.
While some initial leakage was reported and the effectiveness may vary, it's a reliable, clean option for supporting your baby's digestive health and immunity in a quick, simple way.
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Mylicon

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Reduces crying fussiness |
Supports immune health |
Easy to use |
Infants' Mylicon Daily Probiotic Drops are a game-changer for fussy little ones.
Not only do they help reduce crying and fussiness associated with colic, but they also support a healthy immune system by replenishing beneficial gut bacteria.
The drops are super versatile—they can be added to a bottle, applied directly on the breast, or used on a spoon, making them convenient for busy parents.
Plus, with a broad allergen-free formula, you can feel confident about safety.
Just keep in mind they need to be used within 28 days, and the dosage requires some attention.
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MaryRuth Organics Baby Probiotic Drops Probiotic Drops for Newborns

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Supports Gut Health |
Clinically Studied Strains |
Organic and Non-GMO |
MaryRuth's Organic Infant Probiotic Drops stand out with their clinically studied probiotic strains that truly support digestive health and may help reduce fussiness associated with colic.
The fact that they are USDA Organic, Non-GMO, and free from common allergens makes them a trustworthy choice for health-conscious parents.
While some users have noted a bottle clogging issue and that dispensing can be a bit messy, we found the drops easy to administer with proper shaking and patience.
Overall, this probiotic offers a gentle, effective, and natural way to promote your baby's gut health.
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